Inflammatory Joint Diseases and Risk of Cardiovascular Disease in Modern Rheumatology

In this issue of The Journal , Liew, et al present a cross-sectional study comparing the 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with axial spondyloarthritis (axSpA) versus general US population. Their hypothesis was that diagnosis axSpA would be associated higher ASCVD1. They studied participating 2 different cohort studies (followed at University California, San Francisco, and Texas Houston Health Science Center). Altogether, cohorts included both radiographic axSpA/ankylosing spondylitis (AS) nonradiographic axSpA. Patients were followed prospectively regular data collections. ASCVD scores calculated for aged 40–75 years without history available measures blood pressure laboratory cholesterol. Individuals from National Nutrition Examination Survey (NHANES) used as comparator group matched 4:1 to according age, sex, race. After calculating NHANES group, authors subsequently compared prevalence ratio ≥ 7.5% between first whole then AS (sensitivity analyses). The found neither increased nor controls; finding contrast their have scores. As an explanation finding, suggest may underpowered find true difference risk. Alternatively, results reflect … Address correspondence Dr. I.J. Berg, Diakonhjemmet Hospital, Department Rheumatology, Box 23 Vinderen, 0319 Oslo, Norway. Email: ingerjoridberg{at}gmail.com.